Cargando…
A novel far-red fluorescent xenograft model of ovarian carcinoma for preclinical evaluation of HER2-targeted immunotoxins
We have created a novel fluorescent model of a human ovarian carcinoma xenograft overexpressing receptor HER2, a promising molecular target of solid tumors. The model is based on a newly generated SKOV-kat cell line stably expressing far-red fluorescent protein Katushka. Katushka is most suitable fo...
Autores principales: | Zdobnova, Tatiana, Sokolova, Evgeniya, Stremovskiy, Oleg, Karpenko, Dmitry, Telford, William, Turchin, Ilya, Balalaeva, Irina, Deyev, Sergey |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741577/ https://www.ncbi.nlm.nih.gov/pubmed/26436696 |
Ejemplares similares
-
Recombinant Immunotoxin 4D5scFv-PE40 for Targeted Therapy of HER2-Positive Tumors
por: Sokolova, E. A., et al.
Publicado: (2015) -
Spheroids of HER2-Positive Breast Adenocarcinoma for Studying Anticancer Immunotoxins In Vitro
por: Balalaeva, I. V., et al.
Publicado: (2017) -
HER2-specific recombinant immunotoxin 4D5scFv-PE40 passes through retrograde trafficking route and forces cells to enter apoptosis
por: Sokolova, Evgeniya, et al.
Publicado: (2017) -
HER2-Specific Targeted Toxin DARPin-LoPE: Immunogenicity and Antitumor Effect on Intraperitoneal Ovarian Cancer Xenograft Model
por: Sokolova, Evgeniya A., et al.
Publicado: (2019) -
Self-Assembling Complexes of Quantum Dots and scFv Antibodies for Cancer Cell Targeting and Imaging
por: Zdobnova, Tatiana A., et al.
Publicado: (2012)