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Achaete scute-like 2 suppresses CDX2 expression and inhibits intestinal neoplastic epithelial cell differentiation

The role of Achaete scute-like 2 (Ascl2) in colorectal cancer (CRC) cell differentiation is unknown. LS174T, HT-29 and Caco-2 cells have high Ascl2 expression, while Lovo and SW480 cells have low Ascl2 expression. LS174T and HT-29 cells with Ascl2 knockdown were transfected with caudal type homeobox...

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Detalles Bibliográficos
Autores principales: Shang, Yangyang, Pan, Qiong, Chen, Lei, Ye, Jun, Zhong, Xiaoli, Li, Xiaohuan, Meng, Linkuan, Guo, Jin, Tian, Yin, He, Yonghong, Chen, Wensheng, Peng, Zhihong, Wang, Rongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741583/
https://www.ncbi.nlm.nih.gov/pubmed/26307678