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A strategy to combine pathway-targeted low toxicity drugs in ovarian cancer

Serous Ovarian Cancers (SOC) are frequently resistant to programmed cell death. However, here we describe that these programmed death-resistant cells are nonetheless sensitive to agents that modulate autophagy. Cytotoxicity is not dependent upon apoptosis, necroptosis, or autophagy resolution. A scr...

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Detalles Bibliográficos
Autores principales: Delaney, Joe R., Patel, Chandni, McCabe, Katelyn E., Lu, Dan, Davis, Mitzie-Ann, Tancioni, Isabelle, von Schalscha, Tami, Bartakova, Alena, Haft, Carley, Schlaepfer, David D., Stupack, Dwayne G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741591/
https://www.ncbi.nlm.nih.gov/pubmed/26418751