Androgen receptor (AR) suppresses miRNA-145 to promote renal cell carcinoma (RCC) progression independent of VHL status

Mutational inactivation of the VHL tumor suppressor plays key roles in the development of renal cell carcinoma (RCC), and mutated VHL-mediated VEGF induction has become the main target for the current RCC therapy. Here we identified a signal pathway of VEGF induction by androgen receptor (AR)/miRNA-...

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Detalles Bibliográficos
Autores principales: Chen, Yuan, Sun, Yin, Rao, Qun, Xu, Hua, Li, Lei, Chang, Chawnshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741598/
https://www.ncbi.nlm.nih.gov/pubmed/26304926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741598/
https://www.ncbi.nlm.nih.gov/pubmed/26304926

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