Restriction of dietary protein decreases mTORC1 in tumors and somatic tissues of a tumor-bearing mouse xenograft model

Reduced dietary protein intake and intermittent fasting (IF) are both linked to healthy longevity in rodents, and are effective in inhibiting cancer growth. The molecular mechanisms underlying the beneficial effects of chronic protein restriction (PR) and IF are unclear, but may be mediated in part...

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Detalles Bibliográficos
Autores principales: Lamming, Dudley W., Cummings, Nicole E., Rastelli, Antonella L., Gao, Feng, Cava, Edda, Bertozzi, Beatrice, Spelta, Francesco, Pili, Roberto, Fontana, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741600/
https://www.ncbi.nlm.nih.gov/pubmed/26378060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741600/
https://www.ncbi.nlm.nih.gov/pubmed/26378060

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