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Phospho-kinase profile of colorectal tumors guides in the selection of multi-kinase inhibitors

Protein kinases play a central role in the oncogenesis of colorectal tumors and are attractive druggable targets. Detection of activated kinases within a tumor could open avenues for drug selection and optimization of new kinase inhibitors. By using a phosphokinase arrays with human colorectal tumor...

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Detalles Bibliográficos
Autores principales: Serrano-Heras, Gemma, Cuenca-López, María Dolores, Montero, Juan Carlos, Corrales-Sanchez, Verónica, Morales, Jorge Carlos, Núñez, Luz-Elena, Morís, Francisco, Pandiella, Atanasio, Ocaña, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741604/
https://www.ncbi.nlm.nih.gov/pubmed/26418718