Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells

The overexpression of ATP binding cassette (ABC) transporters makes tumor cells simultaneously resistant to several cytotoxic drugs. Impairing the energy metabolism of multidrug resistant (MDR) cells is a promising chemosensitizing strategy, but many metabolic modifiers are too toxic in vivo. We pre...

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Detalles Bibliográficos
Autores principales: Kopecka, Joanna, Porto, Stefania, Lusa, Sara, Gazzano, Elena, Salzano, Giuseppina, Giordano, Antonio, Desiderio, Vincenzo, Ghigo, Dario, Caraglia, Michele, De Rosa, Giuseppe, Riganti, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741618/
https://www.ncbi.nlm.nih.gov/pubmed/26372812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741618/
https://www.ncbi.nlm.nih.gov/pubmed/26372812

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