c-Met inhibitors attenuate tumor growth of small cell hypercalcemic ovarian carcinoma (SCCOHT) populations

A cellular model (SCCOHT-1) of the aggressive small cell hypercalcemic ovarian carcinoma demonstrated constitutive chemokine and growth factor production including HGF. A simultaneous presence of c-Met in 41% SCCOHT-1 cells suggested an autocrine growth mechanism. Expression of c-Met was also observ...

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Detalles Bibliográficos
Autores principales: Otte, Anna, Rauprich, Finn, von der Ohe, Juliane, Yang, Yuanyuan, Kommoss, Friedrich, Feuerhake, Friedrich, Hillemanns, Peter, Hass, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741630/
https://www.ncbi.nlm.nih.gov/pubmed/26436697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741630/
https://www.ncbi.nlm.nih.gov/pubmed/26436697

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