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KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27(kip1)

Epidemiological evidence suggests that elevated androgen levels and genetic variation related to the androgen receptor (AR) increase the risk of endometrial cancer (EC). However, the role of AR in EC is poorly understood. We report that two members of the histone demethylase KDM4 family act as major...

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Detalles Bibliográficos
Autores principales: Qiu, Mei-Ting, Fan, Qiong, Zhu, Zhu, Kwan, Suet-Ying, Chen, Limo, Chen, Jin-Hong, Ying, Zuo-Lin, Zhou, Ye, Gu, Wei, Wang, Li-Hua, Cheng, Wei-Wei, Zeng, Jianfang, Wan, Xiao-Ping, Mok, Samuel C., Wong, Kwong-Kwok, Bao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741634/
https://www.ncbi.nlm.nih.gov/pubmed/26397136