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EPHA4 is overexpressed but not functionally active in Sézary syndrome

EPHA4 belongs to the largest subfamily of receptor tyrosine kinases. In addition to its function during development, overexpression of EPHA4 in tumors has been correlated with increased proliferation, migration and poor survival. Several genome-wide transcription profiling studies have demonstrated...

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Detalles Bibliográficos
Autores principales: Hameetman, Liesbeth, van der Fits, Leslie, Zoutman, Willem H., Out-Luiting, Jacoba J., Siegal, Gregg, de Esch, Iwan J.P., Vermeer, Maarten H., Tensen, Cornelis P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741646/
https://www.ncbi.nlm.nih.gov/pubmed/26376612