Functional signaling pathway analysis of lung adenocarcinomas identifies novel therapeutic targets for KRAS mutant tumors

Little is known about the complex signaling architecture of KRAS and the interconnected RAS-driven protein-protein interactions, especially as it occurs in human clinical specimens. This study explored the activated and interconnected signaling network of KRAS mutant lung adenocarcinomas (AD) to ide...

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Detalles Bibliográficos
Autores principales: Baldelli, Elisa, Bellezza, Guido, Haura, Eric B., Crinó, Lucio, Cress, W. Douglas, Deng, Jianghong, Ludovini, Vienna, Sidoni, Angelo, Schabath, Matthew B., Puma, Francesco, Vannucci, Jacopo, Siggillino, Annamaria, Liotta, Lance A., Petricoin, Emanuel F., Pierobon, Mariaelena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741699/
https://www.ncbi.nlm.nih.gov/pubmed/26468985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741699/
https://www.ncbi.nlm.nih.gov/pubmed/26468985

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