Bortezomib enhances expression of effector molecules in anti-tumor CD8(+) T lymphocytes by promoting Notch-nuclear factor-κB crosstalk

The immunosuppressive tumor microenvironment usurps host antitumor immunity by multiple mechanisms including interference with the Notch system, which is important for various metazoan cell fate decisions and hematopoietic cell differentiation and function. We observed that treatment with the protea...

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Detalles Bibliográficos
Autores principales: Thounaojam, Menaka C., Dudimah, Duafalia F., Pellom, Samuel T., Uzhachenko, Roman V., Carbone, David P., Dikov, Mikhail M., Shanker, Anil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741704/
https://www.ncbi.nlm.nih.gov/pubmed/26431276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741704/
https://www.ncbi.nlm.nih.gov/pubmed/26431276

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