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The search for cis-regulatory driver mutations in cancer genomes

With the advent of high-throughput and relatively inexpensive whole-genome sequencing technology, the focus of cancer research has begun to shift toward analyses of somatic mutations in non-coding cis-regulatory elements of the cancer genome. Cis-regulatory elements play an important role in gene re...

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Detalles Bibliográficos
Autores principales: Poulos, Rebecca C., Sloane, Mathew A., Hesson, Luke B., Wong, Jason W. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741709/
https://www.ncbi.nlm.nih.gov/pubmed/26356674