Na(v)1.5 regulates breast tumor growth and metastatic dissemination in vivo

Voltage-gated Na(+) channels (VGSCs) mediate action potential firing and regulate adhesion and migration in excitable cells. VGSCs are also expressed in cancer cells. In metastatic breast cancer (BCa) cells, the Na(v)1.5 α subunit potentiates migration and invasion. In addition, the VGSC-inhibiting...

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Detalles Bibliográficos
Autores principales: Nelson, Michaela, Yang, Ming, Millican-Slater, Rebecca, Brackenbury, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741739/
https://www.ncbi.nlm.nih.gov/pubmed/26452220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741739/
https://www.ncbi.nlm.nih.gov/pubmed/26452220

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