Deciphering the molecular basis of invasiveness in Sdhb-deficient cells

Metastatic pheochromocytomas and paragangliomas (PPGL) are malignant neuroendocrine tumors frequently associated with germline mutations in the SDHB gene. SDHB-mutated PPGL display a hypermethylator phenotype associated with hallmarks of epithelial-to-mesenchymal transition (EMT). In the present stu...

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Detalles Bibliográficos
Autores principales: Loriot, Céline, Domingues, Mélanie, Berger, Adeline, Menara, Mélanie, Ruel, Maëva, Morin, Aurélie, Castro-Vega, Luis-Jaime, Letouzé, Éric, Martinelli, Cosimo, Bemelmans, Alexis-Pierre, Larue, Lionel, Gimenez-Roqueplo, Anne-Paule, Favier, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741742/
https://www.ncbi.nlm.nih.gov/pubmed/26460615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741742/
https://www.ncbi.nlm.nih.gov/pubmed/26460615

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