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Immature myeloid progenitors promote disease progression in a mouse model of Barrett's-like metaplasia

Cdx2, an intestine specific transcription factor, is expressed in Barrett's esophagus (BE). We sought to determine if esophageal Cdx2 expression would accelerate the onset of metaplasia in the L2-IL-1β transgenic mouse model for Barrett's-like metaplasia. The K14-Cdx2::L2-IL-1β double tran...

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Detalles Bibliográficos
Autores principales: Kong, Jianping, Sai, Hong, Crissey, Mary Ann S., Jhala, Nirag, Falk, Gary W., Ginsberg, Gregory G., Abrams, Julian A., Nakagawa, Hiroshi, Wang, Kenneth, Rustgi, Anil K., Wang, Timothy C., Lynch, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741744/
https://www.ncbi.nlm.nih.gov/pubmed/26460825