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Golgi protein 73 activation of MMP-13 promotes hepatocellular carcinoma cell invasion

Golgi Protein 73 (GP73) is a serum biomarker for hepatocellular carcinoma (HCC), however its role in HCC is not clear. We report that GP73 promotes cell invasion, the hallmark of malignancy, through the upregulation of matrix metalloproteinase-13 (MMP-13). GP73 enhances MMP-13 expression through cAM...

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Detalles Bibliográficos
Autores principales: Jin, Di, Tao, Jun, Li, Dan, Wang, Yanan, Li, Li, Hu, Zhongdong, Zhou, Zhenzhen, Chang, Xiuli, Qu, Chunfeng, Zhang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741783/
https://www.ncbi.nlm.nih.gov/pubmed/26378022