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GLI1 orchestrates CXCR4/CXCR7 signaling to enhance migration and metastasis of breast cancer cells

The up-regulation of chemokine receptors CXCR4 and CXCR7 impacts on the distant metastasis and prognosis of breast cancer, though knowledge about the regulatory mechanism of their expressions is limited. Meanwhile, the GLI transcription factors of Hedgehog signaling have been reported to play a pivo...

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Detalles Bibliográficos
Autores principales: Inaguma, Shingo, Riku, Miho, Ito, Hideaki, Tsunoda, Takumi, Ikeda, Hiroshi, Kasai, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741792/
https://www.ncbi.nlm.nih.gov/pubmed/26413813