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AR-v7 protein expression is regulated by protein kinase and phosphatase

Failure of androgen-targeted therapy and progression of castration-resistant prostate cancer (CRPC) are often attributed to sustained expression of the androgen receptor (AR) and its major splice variant, AR-v7. Although the new generation of anti-androgens such as enzalutamide effectively inhibits...

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Detalles Bibliográficos
Autores principales: Li, Yinan, Xie, Ning, Gleave, Martin E., Rennie, Paul S., Dong, Xuesen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741799/
https://www.ncbi.nlm.nih.gov/pubmed/26378044