Differential expression and biochemical activity of the immune receptor Tim-3 in healthy and malignant human myeloid cells

The T cell immunoglobulin and mucin domain 3 (Tim-3) is a plasma membrane-associated receptor which is involved in a variety of biological responses in human immune cells. It is highly expressed in most acute myeloid leukaemia (AML) cells and therefore may serve as a possible target for AML therapy....

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Detalles Bibliográficos
Autores principales: Silva, Isabel Gonçalves, Gibbs, Bernhard F., Bardelli, Marco, Varani, Luca, Sumbayev, Vadim V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741805/
https://www.ncbi.nlm.nih.gov/pubmed/26413815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741805/
https://www.ncbi.nlm.nih.gov/pubmed/26413815

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