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Differential expression and biochemical activity of the immune receptor Tim-3 in healthy and malignant human myeloid cells
The T cell immunoglobulin and mucin domain 3 (Tim-3) is a plasma membrane-associated receptor which is involved in a variety of biological responses in human immune cells. It is highly expressed in most acute myeloid leukaemia (AML) cells and therefore may serve as a possible target for AML therapy....
Autores principales: | Silva, Isabel Gonçalves, Gibbs, Bernhard F., Bardelli, Marco, Varani, Luca, Sumbayev, Vadim V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741805/ https://www.ncbi.nlm.nih.gov/pubmed/26413815 |
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