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EGFRvIII does not affect radiosensitivity with or without gefitinib treatment in glioblastoma cells

BACKGROUND: Glioblastomas (GBM) are often characterized by an elevated expression of the epidermal growth factor receptor variant III (EGFRvIII). We used GBM cell lines with native EGFRvIII expression to determine whether this EGFR variant affects radiosensitivity with or without EGFR targeting. MET...

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Detalles Bibliográficos
Autores principales: Struve, Nina, Riedel, Matthias, Schulte, Alexander, Rieckmann, Thorsten, Grob, Tobias J., Gal, Andreas, Rothkamm, Kai, Lamszus, Katrin, Petersen, Cordula, Dikomey, Ekkehard, Kriegs, Malte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741808/
https://www.ncbi.nlm.nih.gov/pubmed/26418954