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Targeting the ROR1 and ROR2 receptors in epithelial ovarian cancer inhibits cell migration and invasion

AIM: In recent years, the Wnt signalling pathway has been implicated in epithelial ovarian cancer and its members have potential as diagnostic, prognostic and therapeutic targets. Here we investigated the role of two Wnt receptor tyrosine kinases (RTKs), ROR1 and ROR2, and their putative ligand, Wnt...

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Detalles Bibliográficos
Autores principales: Henry, Claire, Llamosas, Estelle, Knipprath-Mészáros, Alexandra, Schoetzau, Andreas, Obermann, Ellen, Fuenfschilling, Maya, Caduff, Rosemarie, Fink, Daniel, Hacker, Neville, Ward, Robyn, Heinzelmann-Schwarz, Viola, Ford, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741897/
https://www.ncbi.nlm.nih.gov/pubmed/26515598