Activation of sirtuin 1/3 improves vascular hyporeactivity in severe hemorrhagic shock by alleviation of mitochondrial damage

Vascular hyporeactivity is one of the major causes responsible for refractory hypotension and associated mortality in severe hemorrhagic shock. Mitochondrial permeability transition (mPT) pore opening in arteriolar smooth muscle cells (ASMCs) is involved in the pathogenesis of vascular hyporeactivit...

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Detalles Bibliográficos
Autores principales: Li, Pengyun, Meng, Xianzhong, Bian, Huining, Burns, Nana, Zhao, Ke-seng, Song, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741911/
https://www.ncbi.nlm.nih.gov/pubmed/26473372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741911/
https://www.ncbi.nlm.nih.gov/pubmed/26473372

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