Loss of Gata4 in Sertoli cells impairs the spermatogonial stem cell niche and causes germ cell exhaustion by attenuating chemokine signaling

Sertoli cells, the primary somatic cell in the seminiferous epithelium, provide the spermatogonial stem cell (SSC) microenvironment (niche) through physical support and the expression of paracrine factors. However, the regulatory mechanisms within the SSC niche, which is primarily controlled by Sert...

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Detalles Bibliográficos
Autores principales: Chen, Su-Ren, Tang, Ji-Xin, Cheng, Jin-Mei, Li, Jian, Jin, Cheng, Li, Xiao-Yu, Deng, Shou-Long, Zhang, Yan, Wang, Xiu-Xia, Liu, Yi-Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741912/
https://www.ncbi.nlm.nih.gov/pubmed/26473289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741912/
https://www.ncbi.nlm.nih.gov/pubmed/26473289

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