Cargando…

Loss of Gata4 in Sertoli cells impairs the spermatogonial stem cell niche and causes germ cell exhaustion by attenuating chemokine signaling

Sertoli cells, the primary somatic cell in the seminiferous epithelium, provide the spermatogonial stem cell (SSC) microenvironment (niche) through physical support and the expression of paracrine factors. However, the regulatory mechanisms within the SSC niche, which is primarily controlled by Sert...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Su-Ren, Tang, Ji-Xin, Cheng, Jin-Mei, Li, Jian, Jin, Cheng, Li, Xiao-Yu, Deng, Shou-Long, Zhang, Yan, Wang, Xiu-Xia, Liu, Yi-Xun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper: Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741912/ https://www.ncbi.nlm.nih.gov/pubmed/26473289

Ejemplares similares

Sertoli cell ablation and replacement of the spermatogonial niche in mouse
por: Yokonishi, Tetsuhiro, et al.
Publicado: (2020)

WTAP Function in Sertoli Cells Is Essential for Sustaining the Spermatogonial Stem Cell Niche
por: Jia, Gong-Xue, et al.
Publicado: (2020)

Sertoli cell and spermatogonial development in pigs
por: Zheng, Yi, et al.
Publicado: (2022)

Alteration of protein prenylation promotes spermatogonial differentiation and exhausts spermatogonial stem cells in newborn mice
por: Diao, Fan, et al.
Publicado: (2016)

Sertoli Cell-Germ Cell Interactions Within the Niche: Paracrine and Juxtacrine Molecular Communications
por: Hofmann, Marie-Claude, et al.
Publicado: (2022)

Spermatogonial Stem Cell Niche and Spermatogonial Stem Cell Transplantation in Zebrafish
por: Nóbrega, Rafael Henrique, et al.
Publicado: (2010)

Unilateral, Small, Benign, Late-Onset, Large-Cell Calcifying Sertoli Cell Tumor: A Case Report
por: Angerer, Markus, et al.
Publicado: (2023)

A single-nucleus transcriptomic atlas of primate testicular aging reveals exhaustion of the spermatogonial stem cell reservoir and loss of Sertoli cell homeostasis
por: Huang, Daoyuan, et al.
Publicado: (2022)

Spermatogonial Stem Cell Markers and Niche in Equids
por: Costa, Guilherme M. J., et al.
Publicado: (2012)

AIP1-mediated actin disassembly is required for postnatal germ cell migration and spermatogonial stem cell niche establishment
por: Xu, J, et al.
Publicado: (2015)

Melatonin attenuates detrimental effects of diabetes on the niche of mouse spermatogonial stem cells by maintaining Leydig cells
por: Du, Zhaoyu, et al.
Publicado: (2018)

Perturbation of microRNA signalling by doxorubicin in spermatogonial, Leydig and Sertoli cell lines in vitro
por: Akinjo, Oluwajoba O., et al.
Publicado: (2018)

50 years of spermatogenesis: Sertoli cells and their interactions with germ cells
por: Griswold, Michael D
Publicado: (2018)

Mixed germ cell-sex cord-stromal tumor with a concurrent interstitial cell tumor in a ferret
por: INOUE, Saki, et al.
Publicado: (2014)

CTNNB1 Signaling in Sertoli Cells Downregulates Spermatogonial Stem Cell Activity via WNT4
por: Boyer, Alexandre, et al.
Publicado: (2012)

The interaction between Sertoli cells and luekemia inhibitory factor on the propagation and differentiation of spermatogonial stem cells in vitro
por: Rastegar, Tayebeh, et al.
Publicado: (2015)

Melatonin up-regulates the expression of the GATA-4 transcription factor and increases testosterone secretion from Leydig cells through RORα signaling in an in vitro goat spermatogonial stem cell differentiation culture system
por: Deng, Shou-Long, et al.
Publicado: (2017)

Testicular Germ Cell Tumors: Paraneoplastic Syndromes and the Role of Beta-Human Chorionic Gonadotropin
por: Tannous, Toufic, et al.
Publicado: (2021)

Regressed Non-metastatic Germ Cell Tumour: A Case Report and Literature Review
por: Abdalla, Ahmed, et al.
Publicado: (2023)

Exceedingly Rare Bilateral Synchronous Germ Cell Testicular Tumors With Different Histopathological Features
por: Kim, Jong H, et al.
Publicado: (2023)

Effects of Pgam1-mediated glycolysis pathway in Sertoli cells on Spermatogonial stem cells based on transcriptomics and energy metabolomics
por: An, Xuejiao, et al.
Publicado: (2022)

Retinoic acid combined with spermatogonial stem cell conditions facilitate the generation of mouse germ-like cells
por: Dong, Guoyi, et al.
Publicado: (2017)

Dissecting the spermatogonial stem cell niche using spatial transcriptomics
por: Rajachandran, Shreya, et al.
Publicado: (2023)

Comparison of Neonatal and Adult Mice-derived Sertoli Cells in Support of Expansion of Mouse Spermatogonial Stem Cells In vitro
por: Tavakolifar, Faranak, et al.
Publicado: (2012)

Decoding the spermatogonial stem cell niche under physiological and recovery conditions in adult mice and humans
por: Jin, Cheng, et al.
Publicado: (2023)

NICD-mediated notch transduction regulates the different fate of chicken primordial germ cells and spermatogonial stem cells
por: Zuo, Qisheng, et al.
Publicado: (2018)

Effect of Antioxidants and Apoptosis Inhibitors on Cryopreservation of Murine Germ Cells Enriched for Spermatogonial Stem Cells
por: Ha, Seung-Jung, et al.
Publicado: (2016)

Rubicon prevents autophagic degradation of GATA4 to promote Sertoli cell function
por: Yamamuro, Tadashi, et al.
Publicado: (2021)

Role of GATA3 in Early-Stage Urothelial Bladder Carcinoma Local Recurrence
por: Popov, Hristo, et al.
Publicado: (2023)

Comparative Analysis of the Potential for Germ Cell (GC) Differentiation of Bovine Peripheral Blood Derived-Mesenchymal Stem Cells (PB-MSC) and Spermatogonial Stem Cells (SSC) in Co-Culture System with Sertoli Cells (SC)
por: Segunda, Moisés N., et al.
Publicado: (2023)

MiRNA-133b promotes the proliferation of human Sertoli cells through targeting GLI3
por: Yao, Chencheng, et al.
Publicado: (2016)

Retinoic Acid Receptor Alpha Is Essential in Postnatal Sertoli Cells but Not in Germ Cells
por: Condrea, Diana, et al.
Publicado: (2022)

Two distinct Sertoli cell states are regulated via germ cell crosstalk(†)
por: Gewiss, Rachel L, et al.
Publicado: (2021)

C-X-C motif chemokine ligand 10 produced by mouse Sertoli cells in response to mumps virus infection induces male germ cell apoptosis
por: Jiang, Qian, et al.
Publicado: (2017)

Cnot3 is required for male germ cell development and spermatogonial stem cell maintenance
por: Chen, Qing, et al.
Publicado: (2023)

Ovarian mixed germ-cell tumor comprising mature teratoma and embryonal carcinoma in a four-toed hedgehog (Atelerix albiventris)
por: UEDA, Kengo, et al.
Publicado: (2021)

Resveratrol changes spermatogonial stem cells (SSCs) activity and ameliorates their loss in busulfan-induced infertile mouse
por: Wu, Chongyang, et al.
Publicado: (2016)

Sertoli cell‐derived exosomal MicroRNA‐486‐5p regulates differentiation of spermatogonial stem cell through PTEN in mice
por: Li, Quan, et al.
Publicado: (2021)

An Integrative Omics Strategy to Assess the Germ Cell Secretome and to Decipher Sertoli-Germ Cell Crosstalk in the Mammalian Testis
por: Chalmel, Frédéric, et al.
Publicado: (2014)

Unusual Chemotherapeutic Resistant Testicular Embryonal Germ Cell Tumor with Widespread Metastasis in a Case of Klinefelter Syndrome: A Case Report
por: Feroz, Shah Huzaifa, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_phm12r2qrssp5jdsv1pht2boa5