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Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism

Tumor stem cell marker Doublecortin-like kinase1 (DCLK1) is upregulated in several solid tumors. The role of DCLK1 in hepatocellular carcinoma (HCC) is unclear. We immunostained tissues from human livers with HCC, cirrhosis controls (CC), and non-cirrhosis controls (NCC) for DCLK1. Western blot and...

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Detalles Bibliográficos
Autores principales: Sureban, Sripathi M., Madhoun, Mohammad F., May, Randal, Qu, Dongfeng, Ali, Naushad, Fazili, Javid, Weygant, Nathaniel, Chandrakesan, Parthasarathy, Ding, Kai, Lightfoot, Stanley A., Houchen, Courtney W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741924/
https://www.ncbi.nlm.nih.gov/pubmed/26468984