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miR-135b suppresses tumorigenesis in glioblastoma stem-like cells impairing proliferation, migration and self-renewal

Glioblastoma multiforme (GBM) is the most common and fatal malignant adult primary brain tumor. Currently, the overall prognosis for GBM patients remains poor despite advances in neurosurgery and adjuvant treatments. MicroRNAs (miRNAs) contribute to the pathogenesis of various types of tumor, includ...

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Detalles Bibliográficos
Autores principales: Lulli, Valentina, Buccarelli, Mariachiara, Martini, Maurizio, Signore, Michele, Biffoni, Mauro, Giannetti, Stefano, Morgante, Liliana, Marziali, Giovanna, Ilari, Ramona, Pagliuca, Alfredo, Larocca, Luigi Maria, De Maria, Ruggero, Pallini, Roberto, Ricci-Vitiani, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741927/
https://www.ncbi.nlm.nih.gov/pubmed/26437223