Targeting Syndecan-1, a molecule implicated in the process of vasculogenic mimicry, enhances the therapeutic efficacy of the L19-IL2 immunocytokine in human melanoma xenografts

Anti-angiogenic therapy of solid tumors has until now failed to produce the long lasting clinical benefits desired, possibly due to the complexity of the neoangiogenic process. Indeed, a prominent role is played by “vasculogenic” or “vascular” mimicry (VM), a phenomenon in which aggressive cancer ce...

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Detalles Bibliográficos
Autores principales: Orecchia, Paola, Conte, Romana, Balza, Enrica, Pietra, Gabriella, Mingari, Maria Cristina, Carnemolla, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741939/
https://www.ncbi.nlm.nih.gov/pubmed/26460958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741939/
https://www.ncbi.nlm.nih.gov/pubmed/26460958

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