JNJ-26481585 primes rhabdomyosarcoma cells for chemotherapeutics by engaging the mitochondrial pathway of apoptosis

Rhabdomyosarcoma (RMS) is a common soft-tissue sarcoma in childhood with a poor prognosis, highlighting the need for new treatment strategies. Here we identify a synergistic interaction of the second-generation histone deacetylase inhibitor (HDACI) JNJ-26481585 and common chemotherapeutic drugs (i.e...

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Detalles Bibliográficos
Autores principales: Heinicke, Ulrike, Kupka, Johanna, Fulda, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741969/
https://www.ncbi.nlm.nih.gov/pubmed/26473375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741969/
https://www.ncbi.nlm.nih.gov/pubmed/26473375

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