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miRNA-regulated delivery of lincRNA-p21 suppresses β-catenin signaling and tumorigenicity of colorectal cancer stem cells

Cancer stem cells (CSCs) are key cellular targets for effective cancer therapy, due to their critical roles in cancer progression and chemo/radio-resistance. Emerging evidence demonstrates that long non-coding RNAs (lncRNAs) are important players in the biology of cancers. However, it remains unknow...

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Detalles Bibliográficos
Autores principales: Wang, Jun, Lei, Zeng-jie, Guo, Yan, Wang, Tao, Qin, Zhong-yi, Xiao, Hua-liang, Fan, Li-lin, Chen, Dong-feng, Bian, Xiu-wu, Liu, Jia, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741970/
https://www.ncbi.nlm.nih.gov/pubmed/26497997