Epigenetic silencing of HIC1 promotes epithelial-mesenchymal transition and drives progression in esophageal squamous cell carcinoma

Downregulation of the novel tumor suppressor gene HIC1 (hypermethylated in cancer 1) occurs frequently in various tumors where it causes tumor progression and metastasis. In this study, we investigated a role of HIC1 in esophageal squamous cell carcinoma (ESCC) and the underlying mechanisms. Downreg...

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Detalles Bibliográficos
Autores principales: Li, Pei, Liu, Xiang, Dong, Zi-Ming, Ling, Zhi-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741990/
https://www.ncbi.nlm.nih.gov/pubmed/26510908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741990/
https://www.ncbi.nlm.nih.gov/pubmed/26510908

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