Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways

Angiogenesis and epidermal growth factor receptor (EGFR) inhibition has been shown to have anti-tumour efficacy, and enhance the therapeutic effects of cytotoxic chemotherapy in metastatic colorectal cancer. The interplay of signalling alterations and changes in metabolism and hypoxia in tumours fol...

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Detalles Bibliográficos
Autores principales: Greening, David W., Lee, Sze Ting, Ji, Hong, Simpson, Richard J., Rigopoulos, Angela, Murone, Carmel, Fang, Catherine, Gong, Sylvia, O'Keefe, Graeme, Scott, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741991/
https://www.ncbi.nlm.nih.gov/pubmed/26517691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741991/
https://www.ncbi.nlm.nih.gov/pubmed/26517691

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