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Increased metastasis with loss of E2F2 in Myc-driven tumors

In human breast cancer, mortality is associated with metastasis to distant sites. Therefore, it is critical to elucidate the biological mechanisms that underlie tumor progression and metastasis. Using signaling pathway signatures we previously predicted a role for E2F transcription factors in Myc in...

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Detalles Bibliográficos
Autores principales: Yuwanita, Inez, Barnes, Danielle, Monterey, Michael D., O'Reilly, Sandra, Andrechek, Eran R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741994/
https://www.ncbi.nlm.nih.gov/pubmed/26474282