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Interplay between YB-1 and IL-6 promotes the metastatic phenotype in breast cancer cells

Epithelial to mesenchymal transition (EMT) induces cell plasticity and promotes metastasis. The multifunctional oncoprotein Y-box binding protein-1 (YB-1) and the pleiotropic cytokine interleukin 6 (IL-6) have both been implicated in tumor cell metastasis and EMT, but via distinct pathways. Here, we...

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Detalles Bibliográficos
Autores principales: Castellana, Bàrbara, Aasen, Trond, Moreno-Bueno, Gema, Dunn, Sandra E., Ramón y Cajal, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741996/
https://www.ncbi.nlm.nih.gov/pubmed/26512918