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Modification of Caffeic Acid with Pyrrolidine Enhances Antioxidant Ability by Activating AKT/HO-1 Pathway in Heart

Overproduction of free radicals during ischemia/reperfusion (I/R) injury leads to an interest in using antioxidant therapy. Activating an endogenous antioxidant signaling pathway is more important due to the fact that the free radical scavenging behavior in vitro does not always correlate with a cyt...

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Detalles Bibliográficos
Autores principales: Ku, Hui-Chun, Lee, Shih-Yi, Yang, Kai-Chien, Kuo, Yueh-Hsiung, Su, Ming-Jai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742076/
https://www.ncbi.nlm.nih.gov/pubmed/26845693
http://dx.doi.org/10.1371/journal.pone.0148545