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Epigenetic silencing of miR-145-5p contributes to brain metastasis

Brain metastasis is a major cause of morbidity and mortality of lung cancer patients. We assessed whether aberrant expression of specific microRNAs could contribute to brain metastasis. Comparison of primary lung tumors and their matched metastatic brain disseminations identified shared patterns of...

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Detalles Bibliográficos
Autores principales: Donzelli, Sara, Mori, Federica, Bellissimo, Teresa, Sacconi, Andrea, Casini, Beatrice, Frixa, Tania, Roscilli, Giuseppe, Aurisicchio, Luigi, Facciolo, Francesco, Pompili, Alfredo, Carosi, Maria Antonia, Pescarmona, Edoardo, Segatto, Oreste, Pond, Greg, Muti, Paola, Telera, Stefano, Strano, Sabrina, Yarden, Yosef, Blandino, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742098/
https://www.ncbi.nlm.nih.gov/pubmed/26440147