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The ON:OFF switch, σ1R-HINT1 protein, controls GPCR-NMDA receptor cross-regulation: Implications in neurological disorders

In the brain, the histidine triad nucleotide-binding protein 1 (HINT1) and sigma 1 receptors (σ1Rs) coordinate the activity of certain G-protein coupled receptors (GPCRs) with that of glutamate N-methyl-D-aspartate receptors (NMDARs). To determine the role of HINT1-σ1R in the plasticity of GPCR-NMDA...

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Detalles Bibliográficos
Autores principales: Rodríguez-Muñoz, María, Cortés-Montero, Elsa, Pozo-Rodrigálvarez, Andrea, Sánchez-Blázquez, Pilar, Garzón-Niño, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742118/
https://www.ncbi.nlm.nih.gov/pubmed/26461475