DNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-aging

A major issue in aging research is how cellular phenomena affect aging at the systemic level. Emerging evidence suggests that DNA damage response (DDR) signaling is a key mechanism linking DNA damage accumulation, cell senescence, and organism aging. DDR activation in senescent cells promotes acquis...

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Detalles Bibliográficos
Autores principales: Olivieri, Fabiola, Albertini, Maria Cristina, Orciani, Monia, Ceka, Artan, Cricca, Monica, Procopio, Antonio Domenico, Bonafè, Massimiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Review: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742121/
https://www.ncbi.nlm.nih.gov/pubmed/26431329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742121/
https://www.ncbi.nlm.nih.gov/pubmed/26431329

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