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DNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-aging
A major issue in aging research is how cellular phenomena affect aging at the systemic level. Emerging evidence suggests that DNA damage response (DDR) signaling is a key mechanism linking DNA damage accumulation, cell senescence, and organism aging. DDR activation in senescent cells promotes acquis...
Autores principales: | Olivieri, Fabiola, Albertini, Maria Cristina, Orciani, Monia, Ceka, Artan, Cricca, Monica, Procopio, Antonio Domenico, Bonafè, Massimiliano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742121/ https://www.ncbi.nlm.nih.gov/pubmed/26431329 |
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