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MAGI3 negatively regulates Wnt/β-catenin signaling and suppresses malignant phenotypes of glioma cells

Gliomas are the most common primary brain malignancies and are associated with a poor prognosis. Here, we showed that the PDZ domain-containing protein membrane-associated guanylate kinase inverted 3 (MAGI3) was downregulated at the both mRNA and protein levels in human glioma samples. MAGI3 inhibit...

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Detalles Bibliográficos
Autores principales: Ma, Qian, Yang, Ying, Feng, Duiping, Zheng, Shuai, Meng, Ran, Fa, Pengyan, Zhao, Chunjuan, Liu, Hua, Song, Ran, Tao, Tao, Yang, Longyan, Dai, Jie, Wang, Songlin, Jiang, Wen G., He, Junqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742146/
https://www.ncbi.nlm.nih.gov/pubmed/26452219