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Frequent DPH3 promoter mutations in skin cancers

Recent reports suggested frequent occurrence of cancer associated somatic mutations within regulatory elements of the genome. Based on initial exome sequencing of 21 melanomas, we report frequent somatic mutations in skin cancers in a bidirectional promoter of diphthamide biosynthesis 3 (DPH3) and o...

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Detalles Bibliográficos
Autores principales: Denisova, Evgeniya, Heidenreich, Barbara, Nagore, Eduardo, Rachakonda, P. Sivaramakrishna, Hosen, Ismail, Akrap, Ivana, Traves, Víctor, García-Casado, Zaida, López-Guerrero, José Antonio, Requena, Celia, Sanmartin, Onofre, Serra-Guillén, Carlos, Llombart, Beatriz, Guillén, Carlos, Ferrando, Jose, Gimeno, Enrique, Nordheim, Alfred, Hemminki, Kari, Kumar, Rajiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742151/
https://www.ncbi.nlm.nih.gov/pubmed/26416425