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Frequent DPH3 promoter mutations in skin cancers
Recent reports suggested frequent occurrence of cancer associated somatic mutations within regulatory elements of the genome. Based on initial exome sequencing of 21 melanomas, we report frequent somatic mutations in skin cancers in a bidirectional promoter of diphthamide biosynthesis 3 (DPH3) and o...
Autores principales: | Denisova, Evgeniya, Heidenreich, Barbara, Nagore, Eduardo, Rachakonda, P. Sivaramakrishna, Hosen, Ismail, Akrap, Ivana, Traves, Víctor, García-Casado, Zaida, López-Guerrero, José Antonio, Requena, Celia, Sanmartin, Onofre, Serra-Guillén, Carlos, Llombart, Beatriz, Guillén, Carlos, Ferrando, Jose, Gimeno, Enrique, Nordheim, Alfred, Hemminki, Kari, Kumar, Rajiv |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742151/ https://www.ncbi.nlm.nih.gov/pubmed/26416425 |
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