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Septin cooperation with tubulin polyglutamylation contributes to cancer cell adaptation to taxanes

The mechanisms of cancer cell adaptation to the anti-microtubule agents of the taxane family are multifaceted and still poorly understood. Here, in a model of breast cancer cells which display amplified microtubule dynamics to resist Taxol(®), we provide evidence that septin filaments containing hig...

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Detalles Bibliográficos
Autores principales: Froidevaux-Klipfel, Laurence, Targa, Benjamin, Cantaloube, Isabelle, Ahmed-Zaïd, Hayat, Poüs, Christian, Baillet, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742162/
https://www.ncbi.nlm.nih.gov/pubmed/26460824