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Transgenerational inheritance of enhanced susceptibility to radiation-induced medulloblastoma in newborn Ptch1(+/−) mice after paternal irradiation

The hypothesis of transgenerational induction of increased cancer susceptibility after paternal radiation exposure has long been controversial because of inconsistent results and the lack of a mechanistic interpretation. Here, exploiting Ptch1 heterozygous knockout mice, susceptible to spontaneous a...

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Detalles Bibliográficos
Autores principales: Paris, Lorena, Giardullo, Paola, Leonardi, Simona, Tanno, Barbara, Meschini, Roberta, Cordelli, Eugenia, Benassi, Barbara, Longobardi, Maria Grazia, Izzotti, Alberto, Pulliero, Alessandra, Mancuso, Mariateresa, Pacchierotti, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742164/
https://www.ncbi.nlm.nih.gov/pubmed/26452034