Sulfonamide derivative targeting carbonic anhydrase IX as a nuclear imaging probe for colorectal cancer detection in vivo

Hypoxic microenvironment is a common situation in solid tumors. Carbonic anhydrase IX (CA9) is one of the reliable cellular biomarkers of hypoxia. The role of CA9 in colorectal cancer (CRC) remains to be clarified. CA9 inhibitor such as sulfonamides is known to block CA9 activation and reduce tumor...

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Detalles Bibliográficos
Autores principales: Guan, Siao-Syun, Cheng, Chun-Chia, Ho, Ai-Sheng, Wang, Chia-Chi, Luo, Tsai-Yueh, Liao, Tse-Zung, Chang, Jungshan, Wu, Cheng-Tien, Liu, Shing-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742167/
https://www.ncbi.nlm.nih.gov/pubmed/26447758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742167/
https://www.ncbi.nlm.nih.gov/pubmed/26447758

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