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Metformin prevents cancer metastasis by inhibiting M2-like polarization of tumor associated macrophages

Accumulated evidence suggests that M2-like polarized tumor associated macrophages (TAMs) plays an important role in cancer progression and metastasis, establishing TAMs, especially M2-like TAMs as an appealing target for therapy intervention. Here we found that metformin significantly suppressed IL-...

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Detalles Bibliográficos
Autores principales: Ding, Ling, Liang, Guikai, Yao, Zhangting, Zhang, Jieqiong, Liu, Ruiyang, Chen, Huihui, Zhou, Yulu, Wu, Honghai, Yang, Bo, He, Qiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742188/
https://www.ncbi.nlm.nih.gov/pubmed/26497364