Mitotic entry: Non-genetic heterogeneity exposes the requirement for Plk1

The quest to develop novel antimitotic chemotherapy agents has led to the generation of several small molecule inhibitors targeting Plk1, a protein kinase required for multiple aspects of cell division. Previous studies have shown that upon exposure to Plk1 inhibitors, cells enter mitosis, delay bri...

Descripción completa

Detalles Bibliográficos
Autores principales: Aspinall, Claire F., Zheleva, Daniella, Tighe, Anthony, Taylor, Stephen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742190/
https://www.ncbi.nlm.nih.gov/pubmed/26472023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742190/
https://www.ncbi.nlm.nih.gov/pubmed/26472023

Ejemplares similares