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Mitotic entry: Non-genetic heterogeneity exposes the requirement for Plk1
The quest to develop novel antimitotic chemotherapy agents has led to the generation of several small molecule inhibitors targeting Plk1, a protein kinase required for multiple aspects of cell division. Previous studies have shown that upon exposure to Plk1 inhibitors, cells enter mitosis, delay bri...
Autores principales: | Aspinall, Claire F., Zheleva, Daniella, Tighe, Anthony, Taylor, Stephen S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742190/ https://www.ncbi.nlm.nih.gov/pubmed/26472023 |
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