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Identification of drugs as single agents or in combination to prevent carcinoma dissemination in a microfluidic 3D environment

Experiments were performed in a modified microfluidic platform recapitulating part of the in vivo tumor microenvironment by co-culturing carcinoma cell aggregates embedded in a three-dimensional (3D) collagen scaffold with human umbilical vein endothelial cells (HUVECs). HUVECs were seeded in one ch...

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Detalles Bibliográficos
Autores principales: Bai, Jing, Tu, Ting-Yuan, Kim, Choong, Thiery, Jean Paul, Kamm, Roger D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742198/
https://www.ncbi.nlm.nih.gov/pubmed/26474384